News announcement

【职位介绍】

Two postdoctoral positions are available in the Department of Physiology & Biophysics at Case Western Reserve University School of Medicine to study neurodegenerative diseases.

The lab focuses on cellular and molecular mechanisms of neurodegenerative diseases with an emphasis on mitochondrial pathology, metabolism and immune response. We use a combination of in vitro cell culture, in vivo transgenic animal models and patient iPS cells-derived neuron and glia to study the pathogenesis underlying neurodegenerative diseases. Another research focus of the lab is the development of therapeutics for the treatment of human diseases. We have been using the rationally designed peptide inhibitors of protein-protein interactions and high throughput screening to identify mitochondrial enhancers as therapeutic options.

The successful applicants will participate in NIH-funded projects on elucidating the molecular basis of metabolic dysregulation and immune response in neurodegenerative diseases. The applicants must have a PhD and/or MD degree in neuroscience, molecular biology, cell biology, pharmacology, or related field. Candidates with experience in neurodegenerative diseases and transgenic mouse models are highly desired.